Pie chart representations of GO entries occurrence among genes detected in VSa13 and VSa16 cells. Pie charts represent biological processes, molecular function and cellular component GO entries occurrence among differentially expressed genes in control versus mineralized VSa13 and VSa16 cells. Raw data were normalized using the quantile method and a two class SAM test was performed; FDR and FC were lower than 5% and higher than 1.5, respectively. Biological processes GO entries were associated with 19.2% (VSa13) and 16.6% (VSa16) of identified genes; molecular function GO entries were associated with 24.3% (VSa13) and 20.7% (VSa16) of identified genes; and cellular component GO entries were associated to 18.5% (VSa13) and 10.3% (VSa16) of identified genes. GO definitions: BA, biological adhesion; ER, extracellular region; ERA, enzyme regulator activity; MC, macromolecular complex; MCSO, macromolecular complex subunit organization; MTA, molecular transducer activity; OP, organelle part; RS, response to stimulus; SMA, structural molecule; TA, transporter activity. Additional information on GO definition is available in Additional files 1, 2 and 3, Tables S1, S2 and S3.