Table 2.
Heavy metal resistance genes encoded on plasmid pRLO149_83 of R. litoralis
| Accession No. | Gene Name | Annotation | Metal Ions |
|---|---|---|---|
| Copper oxidase systems | |||
| RLO149_p830810 | copper resistance-like protein | Cu2+ | |
| RLO149_p830800 | copper resistance-like protein | Cu2+ | |
| RLO149_p830790 | putative copper resistance protein A | Cu2+ | |
| RLO149_p830650 | copper resistance-like protein | Cu2+ | |
| RLO149_p830640 | cupredoxin-like protein | Cu2+ | |
| RLO149_p830630 | cupredoxin-like protein | Cu2+ | |
| CPx-type ATPases | |||
| RLO149_p830740 | actP | copper-transporting P-type ATPase (EC 3.6.3.4) | Cu+/Ag+ |
| RLO149_p830520 | actP | copper-transporting P-type ATPase (EC 3.6.3.4) | Cu+/Ag+ |
| RLO149_p830380 | cation transport ATPase (P-type) family | Zn2+ | |
| HME-RND-proteins | |||
| RLO149_p830440 | cation efflux system protein CusB-like protein | aerobically Ag+/anaerobically Cu+ | |
| RLO149_p830430 | cusA | cation efflux system protein CusA | aerobically Ag+/anaerobically Cu+ |
| RLO149_p830420 | cusF | cation efflux system protein CusF | aerobically Ag+/anaerobically Cu+ |
| CDF | |||
| RLO149_p830240 | putative cobalt-zinc-cadmium resistance protein CzcD | Zn2+ | |
| Others | |||
| RLO149_p830340 | putative ZIP Zinc transporter | Zn2+ | |
| RLO149_p830610 | putative integral membrane protein DUF6 | ? | |
The proteins are categorized into different heavy metal efflux protein families. Based on sequence similarities the metal ions most likely transported by the efflux systems are indicated in column 4. HME-RND, Heavy Metal Efflux - Resistance-Nodulation-Cell division protein family; CDF, cation diffusion efflux proteins.