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TRIF induces IFN-β and RANTES reporter genes by means of TBK1. MEFs from Tbk1+/+ (filled bars) and Tbk1-/- (empty bars) mice were transfected with IFN-β (Left), RANTES (Center), or ELAM (Right) luciferase reporter genes and cotransfected with a murine TRIF expression vector or left untreated (none). Lysates were assayed for luciferase activity.
