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. 2011 Aug;39(8):1433–1439. doi: 10.1124/dmd.111.038836

TABLE 4.

Significant factors in the multiple linear regression analysis

Backward: P < 0.05 for variables to stay in the model.

Variable Parameter Estimate S.E. F Value P > F
Intercept 5.55931 0.40179 191.44 <0.0001
Weight 0.00431 0.00176 5.99 0.0159
CYP2C9*2 −0.87096 0.19831 19.29 <0.0001
CYP2C9*3 −1.07031 0.29295 13.35 0.0004
VKORC11639G>A −0.81933 0.11751 48.62 <0.0001
CYP4F2 rs2108622 0.37928 0.14053 7.28 0.0080
POR rs2868177 0.35491 0.15440 5.28 0.0234
POR173C>A −0.70359 0.26143 7.24 0.0082
POR208C>T −0.50989 0.21827 5.46 0.0213
Aspirin −0.00287 0.00139 4.27 0.0411