Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The definitions of EC50, the basal response of a constitutively active receptor (B), and the total response of the receptor at a maximally effective concentration of the orthosteric ligand (Tsat) are shown for an agonist (a) and an inverse agonist (b).
