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. 2011 Jul 5;108(29):12001–12006. doi: 10.1073/pnas.1102309108

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Fig. 3. — Embryonic lethal phenotype of Mdmx^C462A/C462A embryos. (A) Dissected Mdmx wild-type and mutant (heterozygous and homozygous) embryos at E9.5. (B) Histology of embryos from Mdmx wild-type and mutant (heterozygous and homozygous) mice at E9.5 with hematoxylin and eosin stain. Arrows indicate where hearts (H), neural ectoderms (N), or somites (S) are located. Analysis of proliferation and apoptosis in embryos at E9.5 from Mdmx^WT/C462A × Mdmx^WT/C462A cross via BrdU incorporation (C) or TUNEL assays (D), respectively.