Table 2.
Analysis of progeny from a MdmxWT/C462A × MdmxWT/C462A cross
Stage | No. of litters | Total no. of embryos | Phenotypes | Genotypes | |||
Normal | Abnormal | MdmxWT/WT | MdmxWT/C462A | MdmxC462A/C462A | |||
E8.5 | 2 | 15 | 9 | 6 | 4 | 6 | 3 |
E9.5 | 4 | 41 | 26 | 15 | 14 | 12 | 11 |
E10.5 | 2 | 20 | 10 | 10 | 8 | 4 | 6 |
E11.5 | 3 | 22 | 15 | 7 | 11 | 5 | 4 |
E12.5 | 2 | 18 | 16 | 2 | 7 | 9 | 1 |
E13.5 | 2 | 20 | 17 | 3 | 3 | 14 | 0 |
Total | 15 | 136 | 93 | 43 | 47 | 50 | 25 |
Many of the abnormal embryos could not be genotyped because of their small size; the ratios are thus skewed.