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. 2011 Jul 5;108(29):12107–12112. doi: 10.1073/pnas.1109718108

Fig. 2.

Fig. 2.

D2R overexpression in the striatum results in decreases in both frequency and amplitude of sIPSCs in layer V pyramidal neurons. (A) Sample traces of the sIPSC recorded from layer V pyramidal neurons in control and D2R-OE mice in the presence of AP5 (50 μM) and NBQX (20 μM). (B) The sIPSC frequency and amplitude recorded from the control and D2R-OE mice (P < 0.05 for both). (C) Sample traces of the mIPSC recorded from layer V pyramidal neurons in control and D2R-OE mice in the presence of TTX. (D) The mIPSCs in both mice genotypes seem to be similar without any statistical difference (n = 5, P = 0.28 for frequency and P = 0.19 for amplitude).