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Changes in synaptic transmissions were reversed after switching off transgenic D2R expression by feeding the mice doxycycline for two weeks. (A) Frequency and amplitude of sEPSCs in control and D2R-OE mice fed for 2 wk with doxycycline (n = 6, P = 0.46 for frequency and P = 0.34 for amplitude). (B) Frequency and amplitude of sIPSCs between control and D2R-OE mice fed for two weeks with doxycycline (n = 6, P = 0.83 for frequency and P = 0.16 for amplitude).
