Fig. 3.

The probability that two individuals carrying an allele of given minor frequency come from different populations, normalized by the expected frequency in a panmictic population, using the seven panels of the exome capture dataset. Sharing decreases dramatically as frequency approaches zero. The reduction in sharing at 50% frequency in some population pairs is caused by low overall numbers in that bin, and a single site (rs6662929) that exhibits inconsistent calls between different calling platforms and most likely has an incorrect homozygous reference call in some populations. Sites were binned by frequency: dots indicate the center of each bin, and solid lines are to guide the eye. Note that singletons are not shown, because there can be no sharing for such sites.