Table 1.
Comparison of clinical characteristics between the remission and nonremission groups during IT and at 1-year follow-up
Variable | Total | Remission group | Nonremission group | P |
---|---|---|---|---|
n | 48 | 21 | 27 | |
Sex | ||||
Male | 34 | 15 | 19 | |
Female | 14 | 6 | 8 | |
Age (years) | 50.6 ± 7.9 | 49.4 ± 8.8 | 51.5 ± 7.1 | 0.376 |
BMI (kg/m2) | ||||
Before therapy | 25.7 ± 3.3 | 26.3 ± 3.8 | 25.3 ± 2.9 | 0.326 |
After therapy | 25.6 ± 3.1 | 26.0 ± 3.3 | 25.2 ± 2.9 | 0.393 |
At 1 year | 25.2 ± 3.3 | 25.2 ± 3.5 | 25.2 ± 3.2 | 0.974 |
FPG (mmol/L) | ||||
Before therapy | 11.5 ± 2.8 | 11.7 ± 2.9 | 11.7 ± 2.4 | 0.993 |
After therapy | 7.5 ± 2.1* | 6.2 ± 0.8* | 8.5 ± 2.2* | 0.000 |
At 1 year | 6.8 ± 1.4* | 6.3 ± 1.3* | 7.5 ± 1.4* | 0.011 |
PPG (mmol/L) | ||||
Before therapy | 14.8 ± 5.8 | 15.1 ± 6.9 | 14.5 ± 4.9 | 0.721 |
After therapy | 7.6 ± 3.1* | 6.1 ± 1.5* | 8.8 ± 3.4* | 0.002 |
At 1 year | 7.7 ± 2.7* | 6.5 ± 1.78* | 9.2 ± 2.9* | 0.001 |
TG (mmol/L) | ||||
Before therapy | 2.0 ± 1.0 | 1.7 ± 0.5 | 2.2 ± 1.3 | 0.073 |
After therapy | 1.5 ± 0.8* | 1.2 ± 0.4* | 1.7 ± 1.0* | 0.040 |
At 1 year | 1.6 ± 0.7† | 1.5 ± 0.7‡ | 1.6 ± 0.8† | 0.751 |
TC (mmol/L) | ||||
Before therapy | 5.0 ± 1.0 | 4.9 ± 1.0 | 5.1 ± 0.9 | 0.442 |
After therapy | 4.6 ± 0.9* | 4.5 ± 0.9 | 4.7 ± 0.8† | 0.601 |
At 1 year | 4.9 ± 0.9 | 4.7 ± 0.8‡ | 5.2 ± 0.9§ | 0.047 |
HDL (mmol/L) | ||||
Before therapy | 1.2 ± 0.3 | 1.2 ± 0.2 | 1.2 ± 0.3 | 0.578 |
After therapy | 1.3 ± 0.3* | 1.2 ± 0.3† | 1.3 ± 0.4† | 0.515 |
At 1 year | 1.3 ± 0.4 | 1.2 ± 0.2 | 1.4 ± 0.5 | 0.189 |
LDL (mmol/L) | ||||
Before therapy | 3.0 ± 0.8 | 3.2 ± 0.8 | 3.0 ± 0.8 | 0.408 |
After therapy | 2.7 ± 0.8* | 2.8 ± 0.7† | 2.6 ± 0.8* | 0.345 |
At 1 year | 2.8 ± 0.8* | 2.8 ± 0.7* | 2.9 ± 0.9 | 0.850 |
FFA (mmol/L) | ||||
Before therapy | 0.7 ± 0.3 | 0.7 ± 0.3 | 0.7 ± 0.2 | 0.462 |
After therapy | 0.7 ± 0.2 | 0.7 ± 0.2 | 0.6 ± 0.2 | 0.745 |
A1C (%) | ||||
Before therapy | 10.0 ± 2.2 | 10.5 ± 2.3 | 9.7 ± 2.0 | 0.184 |
After therapy | 7.9 ± 1.5* | 8.1 ± 1.6* | 7.7 ± 1.4* | 0.357 |
At 1 year | 6.5 ± 0.7*§ | 6.2 ± 0.7*§ | 6.8 ± 0.6* | 0.004 |
Categorical data are expressed as number and continuous data as means ± SD. P value for remission vs. nonremission group.
*P < 0.01 vs. before therapy.
†P < 0.05 vs. before therapy.
‡P < 0.05 vs. after therapy.
§P < 0.01 vs. after therapy.