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. 2011 Jul 18;60(8):2051–2060. doi: 10.2337/db11-0121

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© 2011 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 1. — Production of ATP by isolated human skeletal muscle mitochondria. ATP production was measured in isolated skeletal muscle mitochondria during state 1 (no added substrates) and by using substrates succinate plus rotenone (S/R), glutamate plus malate (G/M), and pyruvate plus malate (P/M) in (A) younger and older (NGT + IGT) subjects and (B) younger, older with NGT, and older with IGT subjects. Data are means ± SE. *P < 0.05 vs. younger group.