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. 2011 Jul 22;6(7):e22013. doi: 10.1371/journal.pone.0022013

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Xu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(a) Location of the bound ligands in YiiX and BcPPNE with respect to the conserved catalytic triads. BcPPNE and YiiX were superposed using their catalytic triads. (b) A proposed chemical function for these enzymes where YiiX and BcPPNE cleave the amide linkage between a fatty acid and an amino acid (R1 = polycarbon chain, R2 = side-chain or H, R3 = peptide or OH).