Table 1. Baseline characteristics and sPLA2-IIa concentrations and activities in patients with stable coronary heart disease.
sPLA2-IIa concentration (ng/mL) | sPLA2-IIa activity (nmol/mL/min) | ||||||
Participant characteristic | N | % | Median | Inter-quartile range | Median | Inter-quartile range | |
Overall populationa | 1012 | 100 | 2.50 | 1.45–4.86 | 1.21 | 0.93–1.58 | |
Age at baseline | 30–39 years | 20 | 2 | 1.47 | 0.92–1.91 | 0.95 | 0.76–1.22 |
40–49 years | 125 | 12 | 1.71 | 1.10–3.51 | 1.07 | 0.89–1.41 | |
50–59 years | 292 | 29 | 2.08 | 1.31–3.91 | 1.12 | 0.87–1.44 | |
60–70 years | 575 | 57 | 2.99 | 1.71–5.63 | 1.30 | 0.97–1.70 | |
Sex | Female | 152 | 15 | 4.99 | 2.20–8.21 | 1.53 | 1.17–2.15 |
Male | 860 | 85 | 2.33 | 1.39–4.20 | 1.16 | 0.91–1.51 | |
Patient group | Acute coronary syndrome | 127 | 13 | 2.00 | 1.26–3.81 | 1.11 | 0.93–1.39 |
Coronary intervention | 296 | 29 | 2.77 | 1.69–5.36 | 1.25 | 0.94–1.68 | |
Myocardial infarction | 589 | 58 | 2.48 | 1.40–4.68 | 1.21 | 0.92–1.57 | |
Body mass index | ≤25 kg/m2 | 285 | 28 | 2.47 | 1.44–4.99 | 1.16 | 0.92–1.53 |
>25–30 kg/m2 | 569 | 56 | 2.41 | 1.44–4.61 | 1.21 | 0.91–1.55 | |
>30 kg/m2 | 157 | 16 | 3.14 | 1.49–5.98 | 1.35 | 1.01–1.79 | |
Disease history | Diabetes mellitus | 177 | 18 | 3.45 | 1.80–6.26 | 1.35 | 1.05–1.76 |
Hypertension | 564 | 56 | 2.77 | 1.54–5.47 | 1.26 | 0.94–1.67 | |
Discharge prescriptions | ACE-inhibitor | 535 | 53 | 2.63 | 1.46–4.81 | 1.22 | 0.90–1.60 |
Lipid-lowering drugs | 780 | 77 | 2.33 | 1.41–4.47 | 1.19 | 0.92–1.53 | |
Smoking history | Never | 316 | 31 | 2.51 | 1.48–5.49 | 1.24 | 0.94–1.66 |
Formerly | 645 | 64 | 2.48 | 1.42–4.63 | 1.20 | 0.92–1.56 | |
Currently | 51 | 5 | 2.66 | 1.73–5.09 | 1.16 | 0.95–1.41 |
N and percentages refer to the subjects with concentration measurements available. Activity measurements were missing for 22 of these.