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. 2011 Jul 22;6(7):e22429. doi: 10.1371/journal.pone.0022429

Table 1. Detection of the expression levels of three major types of MDR proteins in cultured cell lines using immunostaining with monoclonal antibodies and a flow cytometry assay.

Pgp Staining [C219] MRP1 Staining [QCRL1] BCRP/ABCG2 Staining[MM0047-2J39]
CHO K1 0.29±0.3 0.59±0.2 0.74±0.3
A549 0.12±0.02 0.63±0.3 0.57±0.2
HeLa 0.06±0.01 0.10±0.03 0.14±0.01
HL-60 0.13±0.07 0.22±0.07 0.17±0.09
HL-60/MX1 0.11±0.05 0.31±0.04 0.83±0.01
HCT-15 0.28±0.2 0.60±0.13 0.07±0.02
HepG2 0.18±0.05 0.58±0.06 0.14±0.001

Average D values (± SEM) for three representative experiments are presented.