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. 2011 Jul 22;6(7):e22429. doi: 10.1371/journal.pone.0022429

Table 4. Examples of multiplex (dual) probe treatment for MDR activity profiling in the CHO K1 cell line.

Probes Detection Channel D-values Post Inhibitor Treatment(compared to uninhibited cells
CsA Verapamil MK-571 FTC
eFluxx-ID® Green FITC 0.94 0.9 0.98 0.56
Pheophorbide A PerCP 0.25 0.14 0.15 0.33
eFluxx-ID® Gold PE 0.89 0.94 0.96 0.51
Pheophorbide A PerCP 0.25 0.11 0.14 0.34
eFluxx-ID® Gold PE 0.84 0.82 0.96 0.44
DiOC2(3) FITC 0.94 0.96 0.13 0.16
eFluxx-ID® Gold PE 0.9 0.94 0.85 0.53
CMFDA FITC 0.49 0.1 0.91 0.06

(Average D values for three representative experiments are provided as characteristics of MDR, with SD not exceeding 10% for each value).