Figure 4. Effect of CysLT₁ receptor antagonists, montelukast, pranlukast, and zafirlukast on UDP-evoked [Ca²⁺]_i responses.

(A) Cells were stimulated with UDP in the absence (control) or presence of different concentrations of CysLT₁ receptor antagonists applied 10 min prior to the addition of UDP (100 µM). (B) The UDP-evoked [Ca²⁺]_i responses were inhibited by different concentrations of an IP₃ receptor antagonist, XeC, or a PLC inhibitor, U73122. Each column represents the mean ± S.E. (n = 4–6). (*, p<0.05, one-way ANOVA with Bonferroni post-hoc test compared with control).