Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Jun 28;10:78. doi: 10.1186/1476-4598-10-78

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright ©2011 Joshi et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Cancer cells expressing high levels of Bcl-2 are resistant to apoptosis induced by MiTMABs. A-B, Asynchronously growing HeLa, HT29, SW480, MCF-7 and H460 cells were treated with the indicated concentration of OcTMAB for 48 h. Cells containing <2N DNA content (mean ± S.D. from two independent experiments) were determined by flow cytometry (A) and the presence of cleaved PARP was assessed by immunoblotting (B). C, Expression levels of the Bcl-2 family members, Bcl-2, Mcl-1 and Bcl-XL, were assessed and compared in the indicated cancer cell lines by immunoblotting. β-actin served as a loading control.