Table 6.
Nine genes highlighted as XLMR candidates by both the annotation and sequence motif method
| HGNC symbol | Description | Location | Function |
|---|---|---|---|
| FAM156A | Family with sequence similarity 156, member A | Xp11.23 | Function Unknown |
| FAM156B | Family with sequence similarity 156, member B | Xp11.22 | Function Unknown |
| UXT | Ubiquitously-expressed transcript | Xp11.23-p11.22 | Plays a role in facilitating receptor-induced transcriptional activation [83] |
| TBL1X | Transducin (beta)-like 1X-linked | Xp22.3 | Plays an essential role in transcription activation mediated by nuclear receptors [84] |
| MAGED4 | Melanoma antigen family D, 4 | Xp11 | Mainly tumour cell proliferation [85] |
| MAGED4B | Melanoma antigen family D, 4B | Xp11 | Mainly tumour cell proliferation [85] |
| ZC4H2 | Zinc finger, C4H2 domain containing | Xq11.1 |
Hepatocellular carcinoma-associated antigen [38] |
| APLN | Apelin | Xq25 | Neuropeptide involved in the regulation of body fluid homeostasis and cardiovascular functions [86] |
| RAP2C | Member of RAS oncogene family | Xq25 | Involved in serum response element mediated gene transcription [64] |