. Author manuscript; available in PMC: 2011 Jul 22.

Published in final edited form as: Am Heart J. 2011 Jan;161(1):131–137. doi: 10.1016/j.ahj.2010.09.015

Table IV.

Late-onset extracardiac conditions

	Nonsyndromic group (n = 112)	Syndromic group (n = 56)	22q11DS reference group (n = 39)	P value (nonsyndromic vs syndromic groups)
Any neuropsychiatric disorder	19 (17%)	18 (32%)	20 (51%)	.03
Seizures	7 (6%)	8 (14%)	8 (21%)	.09
ADD/ADHD	0	6 (11%)	2 (5%)	.001
Schizophrenia	0	2 (4%)	4 (10%)	.11
Anxiety and/or depression	12 (11%)	5 (9%)	11 (28%)	.72
Any endocrine disorder	4 (4%)	12 (21%)	19 (49%)	<.001
Thyroid dysfunction	4 (4%)	11 (20%)	8 (21%)	.001
Hypocalcemia and/or hypoparathyroidism	0	1 (2%)	17 (44%)	.33
Recurrent otitis media	13 (12%)	13 (23%)	15 (38%)	.05
Hearing deficit	0	11 (20%)	10 (26%)	<.001
In the absence of otitis media	0	3 (5%)	2 (5%)	.04