Table 3.
Exposure to maternal-fetal composite Rh/ABO incompatibility and regional volumetric brain outcomes in control subjects
| Brain region/structure | Volume (cm3) | P-value from Gamma modelA | |||
|---|---|---|---|---|---|
| Exposed control subjects (n=4) | Unexposed control subjects (n=17) | ||||
| Mean | SD | Mean | SD | ||
| Cortical Gray Matter | 664.60 | 56.64 | 665.15 | 74.43 | .4740 |
| Dorsolateral Prefrontal Cortex Left | 13.11 | 2.55 | 14.06 | 1.85 | .1784 |
| Dorsolateral Prefrontal Cortex Right | 13.24 | 2.46 | 14.17 | 1.76 | .1002 |
| Orbitofrontal Cortex Left | 19.27 | 4.23 | 20.83 | 4.03 | .3671 |
| Orbitofrontal Cortex Right | 18.92 | 4.30 | 20.92 | 3.63 | .1727 |
| Inferior Frontal Cortex Left | 10.31 | 1.47 | 11.47 | 1.45 | .0162 |
| Inferior Frontal Cortex Right | 10.26 | 1.01 | 11.32 | 1.48 | .0136 |
| Superior Temporal Gyrus Left | 13.48 | 1.61 | 14.06 | 1.91 | .2468 |
| Superior Temporal Gyrus Right | 13.74 | 1.09 | 14.23 | 1.78 | .1885 |
| Ventricular CSF | 29.06 | 7.75 | 27.07 | 8.91 | .6603 |
| Sulcal CSF | 173.88 | 9.97 | 178.87 | 37.05 | .6521 |
| Subcortical Gray Matter | 4.65 | 0.56 | 4.40 | 1.13 | .6880 |
| Total Hippocampus LeftB | 4354.26 | 649.91 | 3656.74 | 307.79 | <.0001 |
| Total Hippocampus RightB | 4543.33 | 869.11 | 3948.63 | 359.42 | .0105 |
| Caudate Left | 5.08 | 0.67 | 4.89 | 0.62 | .5268 |
| Caudate Right | 5.25 | 0.74 | 5.03 | 0.71 | .4214 |
| Putamen Left | 5.79 | 0.72 | 5.38 | 0.68 | .1720 |
| Putamen Right | 5.80 | 0.52 | 5.26 | 0.71 | .0163 |
| Thalamus Left | 6.93 | 0.88 | 6.47 | 0.65 | .2075 |
| Thalamus Right | 6.78 | 0.78 | 6.39 | 0.56 | .2033 |
| White Matter | 594.93 | 70.25 | 574.79 | 65.64 | .5516 |
| Intracranial | 1502.92 | 119.98 | 1484.04 | 154.10 | .8136C |
A
Adjusted for intracranial volume (cm3)
B
Measured in mm3
C
P value without adjustment for intracranial volume