Figure 6.
Influence of different extinction schedules on the magnitude of reinstatement of place preference and locomotor activity. a. Extinction following reconditioning by descending doses of cocaine resulted in a lower level of place preference reinstatement compared to extinction by saline reconditioning (*p<0.05). Extinction following reconditioning by the descending schedule of 8,4,2 and 1mg/kg resulted in lower level of reinstatement compared to the schedule of 8,4,2 and 0mg/kg cocaine (#p<0.05). b. The mean ±SEM of activity counts recorded during the 20 min test session. No significant differences between the three groups were observed.