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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Biometrics. 2011 Apr 19;67(4):1271–1284. doi: 10.1111/j.1541-0420.2011.01598.x

Table 1.

Results of the simulation study described in Section 5. Displayed are the empirical size (c = 0) and power (c = 2,…, 8) of the proposed garrote kernel machine (GKM) test using the two-way interaction kernel (KInt), the Gaussian kernel (KGauss), the PCA based test statistics Tn and Tn (KGauss,PCA1 and KGauss,PCA2) using the Gaussian kernel as in Section 3.3, and the usual F-test for different settings with n = 50 and M = 5. Also presented, for the linear cases (h1(·) and h2(·)), are the results for the ideal classical score tests assuming the direction of the alternative is known. The nominal level was set be α = 0.05.

Test r = 0.0 r = 0.2 r = 0.5

c = 0 c = 2 c = 4 c = 6 c = 8 c = 0 c = 2 c = 4 c = 6 c = 8 c = 0 c = 2 c = 4 c = 6 c = 8
h1(·) F-test 0.049 0.142 0.409 0.723 0.940 0.042 0.109 0.356 0.703 0.931 0.047 0.095 0.223 0.494 0.765
KInt 0.049 0.141 0.435 0.757 0.933 0.042 0.164 0.446 0.771 0.955 0.049 0.127 0.294 0.572 0.819
KGauss 0.048 0.233 0.685 0.926 0.991 0.050 0.274 0.678 0.941 0.990 0.051 0.236 0.541 0.847 0.977
KGauss,PCA1 0.049 0.228 0.665 0.915 0.993 0.055 0.267 0.661 0.927 0.990 0.050 0.197 0.502 0.794 0.948
KGauss,PCA2 0.049 0.238 0.675 0.917 0.992 0.058 0.277 0.671 0.924 0.991 0.055 0.207 0.552 0.804 0.958
Score test 0.054 0.279 0.726 0.940 0.993 0.054 0.255 0.685 0.925 0.994 0.051 0.221 0.594 0.864 0.970

h2(·) F-test 0.049 0.143 0.417 0.793 0.945 0.042 0.134 0.446 0.794 0.963 0.047 0.107 0.332 0.661 0.881
KInt 0.049 0.154 0.474 0.807 0.921 0.042 0.208 0.582 0.857 0.967 0.049 0.189 0.509 0.777 0.925
KGauss 0.048 0.248 0.665 0.933 0.982 0.050 0.263 0.682 0.917 0.987 0.051 0.230 0.548 0.808 0.938
KGauss,PCA1 0.049 0.242 0.658 0.920 0.988 0.055 0.278 0.658 0.909 0.982 0.050 0.227 0.580 0.828 0.945
KGauss,PCA2 0.049 0.248 0.665 0.927 0.982 0.058 0.267 0.681 0.926 0.981 0.055 0.237 0.582 0.824 0.932
Score test 0.054 0.354 0.881 0.972 0.991 0.054 0.453 0.889 0.983 0.997 0.051 0.637 0.954 0.996 1.000

h3(·) F-test 0.058 0.083 0.178 0.356 0.544 0.049 0.081 0.137 0.249 0.404 0.056 0.059 0.077 0.149 0.217
KInt 0.044 0.081 0.213 0.377 0.562 0.046 0.077 0.187 0.330 0.487 0.046 0.067 0.113 0.192 0.290
KGauss 0.047 0.112 0.351 0.615 0.821 0.051 0.131 0.319 0.581 0.793 0.050 0.117 0.258 0.423 0.599
KGauss,PCA1 0.052 0.128 0.341 0.583 0.801 0.052 0.132 0.325 0.545 0.749 0.050 0.107 0.232 0.380 0.539
KGauss,PCA2 0.052 0.130 0.344 0.593 0.820 0.052 0.130 0.328 0.555 0.759 0.050 0.116 0.242 0.401 0.559

h4(·) F-test 0.058 0.076 0.134 0.293 0.483 0.049 0.071 0.116 0.225 0.389 0.056 0.067 0.083 0.107 0.194
KInt 0.044 0.066 0.145 0.314 0.527 0.046 0.082 0.152 0.301 0.493 0.046 0.074 0.100 0.155 0.279
KGauss 0.047 0.100 0.268 0.571 0.804 0.051 0.122 0.274 0.540 0.734 0.050 0.108 0.225 0.357 0.510
KGauss,PCA1 0.052 0.112 0.254 0.541 0.795 0.052 0.122 0.273 0.498 0.702 0.050 0.101 0.205 0.322 0.498
KGauss,PCA2 0.052 0.111 0.264 0.551 0.799 0.052 0.121 0.264 0.501 0.713 0.050 0.102 0.209 0.337 0.508