Figure 6.

MCT1 is expressed in the epithelial compartment of human breast cancers. Note that only epithelial cancer cells express MCT1 in human breast tumor samples. Two representative images are shown. Both clearly show that MCT1 staining is present in the tumor epithelial cells, but is absent in the surrounding stroma. Panel (A) shows DCIS-like lesions and the surrounding MCT1(+) epithelial cancer cells. Panel (B) shows that MCT1 staining identifies the epithelial cancer cells within the “cancer cell nests.” The original magnifications for (A and B) are 40× and 60×, respectively.