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. 2004 Jan 1;18(1):12–16. doi: 10.1101/gad.1164804

Figure 4.

Figure 4.

Calorie restriction in pnc1Δ mutants. (A) Calorie restriction slightly extends life span in a pnc1Δ mutant. (B) Overexpressing Nnt1 restores the full life-span extension by calorie restriction in a pnc1Δ mutant. Average life spans on 2% glucose: pnc1Δ + vector, 20.9; + vector, 20.16; Δpnc1 +Nnt1-oe, 21.6. Average life spans on 0.5% glucose: pnc1Δ + vector, 23.9; + vector, 27.3; pnc1Δ +Nnt1-oe, 28. (+ vector) cells carrying a control vector ppp35; (+Nnt1-oe) cells overexpressing Nnt1. pnc1Δ was derived from PSY316.