Table 2. Regression of Leucocyte Telomere Length on log (aldosterone) and log (renin) conjointly, and on log (renin-aldosterone ratio).

		All Participants			Non-Hypertensive			Hypertensive
Model, adjustment	Variable	Beta	SE	P-value	Beta	SE	P-value	Beta	SE	P-value
Incorporating Aldosterone and renin conjointly
age, sex	log (aldosterone)	0.082	0.03	0.004	0.063	0.04	0.15	0.092	0.04	0.02
	log (renin)	-0.039	0.02	0.012	-0.009	0.03	0.77	-0.053	0.02	0.003
Multivariable	log (aldosterone)	0.099	0.03	0.002	0.058	0.05	0.22	0.134	0.04	0.002
	log (renin)	-0.038	0.02	0.036	0.001	0.03	0.99	-0.060	0.02	0.005
Incorporating the Renin-aldosterone ratio
Age, sex	log (ratio)	-0.047	0.02	0.002	-0.022	0.03	0.45	-0.058	0.02	<0.001
Multivariable	log (ratio)	-0.049	0.02	0.003	-0.014	0.03	0.67	-0.072	0.02	<0.001

multivariable models adjusted for age, sex, systolic BP, diastolic BP, HTN treatment (where appropriate), current smoking status, diabetes, serum creatinine, urine sodium/creatinine ratio, body mass index, hormone replacement therapy.

Beta is the regression coefficient per unit increase in log(predictor). SE = standard error of beta.