Table 1.
Effect of zinc on cytokine production in HUT-78 Cells1
Cytokine | No stimulation | PMA/PHA | PMA/Ionomycin | |||
---|---|---|---|---|---|---|
Zn− | Zn+ | Zn− | Zn+ | Zn− | Zn+ | |
IL-2 | 14.3±4.52 | 12.0±5.2 | 145.1±18.5 | 338.9±18.63 | 446.5±147.7 | 1199.5±35.33 |
IFN-γ | 7.7±4.2 | 10.1±0.8 | 5.3±4.2 | 20.3±1.63 | 7.7±0.8 | 44.0±8.33 |
Zinc-treated HUT-78 cells were stimulated with PHA (10 μg/mL)/PMA (5 ng/mL) or PHA (5 ng/mL)/ionomycin (1 μg/mL) for 6h.
Mean± S.D. pg/ml cytokine generated;
p= ≤0.05 difference between cells maintained in 1 μM Zn vs 15 μM Zn media (n=3).