Table 2.
Resting heart rate and the effect of metipranolol after atropine administration on the heart rate in diabetic and control female rats.
| Months after STZ | Resting heart rate (min−1) | Effect of MP after ATR (min−1) | ||
|---|---|---|---|---|
| Control (n = 6) | STZ (n = 6) | Control (n = 6) | STZ (n = 5) | |
| 1 | 345 ± 8 | 280 ± 6* | −122 ± 7 | −10 ± 8* |
| 2 | 352 ± 9 | 252 ± 7* | −130 ± 8 | −8 ± 5* |
| 4 | 355 ± 7 | 238 ± 7* | −92 ± 5 | −1 ± 5* |
| 22 | 345 ± 10 | 309 ± 11* | −116 ± 9 | −105 ± 11# |
Values are means ± SEM; STZ: streptozotocin; MP: metipranolol; ATR: atropine; *significantly different from value in control group (P < 0.05); #significantly different from STZ1 value P < 0.05.