Table 1.
ced-4-dependent reduction of cell size in tfg-1(RNAi) mutants.
| Genotype | L4440(RNAi) | tfg-1(RNAi) | |||
|---|---|---|---|---|---|
| Number of muscle | WT | 94.6 ± 0.9 | (n=15) | 94.2 ± 1.9 | (n=15) |
| cells | |||||
| Muscle cell size | WT | 1709.2 ± 224.9 | (n=27) | 679 ± 137.9 | (n=42) ** |
| (µm2) * | ced-4(n1162) | 1322.5 ± 282 | (n=50) | 1254.4 ± 237.5 | (n=56) |
| Muscle nucleus size | WT | 79.7 ± 15.8 | (n=27) | 46.3 ± 9.7 | (n=42) ** |
| (µm2) * | ced-4(n1162) | 71.2 ± 14.9 | (n=50) | 69.1 ± 14.3 | (n=56) |
| Total cell number | WT | 941.3 ± 43.6 | (n=27) | 938.7 ± 44.7 | (n=25) |
RNAi was performed by feeding with either a control feeder (L4440, carrying an uninserted plasmid) or a tfg-1 RNAi feeder. Muscle cell and nucleus size were determined as the area of the largest section through the cell.
Student t test, p<0.01.