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Functional activity of bidirectional and random promoters. (A) The distribution of the ratios of promoter strength in the forward and reverse directions for 56 random nonbidirectional promoters. (B) The distribution of the ratios of promoter strength in the forward and reverse directions for 258 bidirectional promoters. Based on a Kolmogorov-Smirnov test, these two distributions are significantly different (P < 0.001).
