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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Curr Cancer Drug Targets. 2011 Jun;11(5):560–571. doi: 10.2174/156800911795655958

Fig. (4). AR mediates malignant growth in nude mice xenografts.

Fig. (4)

A). Effect of AR-siRNA on SW480 xenografts. An aliquot of 2 × 106 SW480 cells in 100 μL PBS was injected s.c. into one flank of each nu/nu nude mouse. When tumors reached a cross-sectional area of 45 mm2, animals were treated with PBS, scrambled siRNA, or AR-siRNA. At different days, tumors were measured in two dimensions using calipers. B). Photographs of animals taken at different days of tumor progression are shown. [Reproduced with permission from R Tammali et al.: Cancer Res. 66 (19): 9705 – 9713, 2006; Ref.: 25)