Table 3. Univariate and multivariate analyses for survival.
|
Cox univariate
|
Cox multivariate
|
|||||||
|---|---|---|---|---|---|---|---|---|
| N a | Hazard ratio | 95% CI | P-value | N a | Hazard ratio | 95% CI | P-value | |
| A: IPC set, PFS analysis | ||||||||
| Age (years) | 35 | 1.02 | 0.98–1.05 | 0.36 | ||||
| Grade 3 (vs 1+2) | 34 | 1.42 | 0.59–3.43 | 0.43 | ||||
| FIGO stage (IV vs others) | 35 | 22.9 | 5.16–101 | 3.80E-05 | 34 | 8.34 | 1.93–36.1 | 4.60E-03 |
| Taxane without (vs with) | 35 | 1.83 | 0.82–4.07 | 0.14 | ||||
| Non-optimal surgery (vs optimal) | 34 | 3.35 | 1.34–8.38 | 9.80E-03 | 34 | 2.36 | 0.89–6.26 | 0.09 |
| OPM Unfavourable (vs Favourable) | 35 | 14.3 | 3.87–53.1 | 6.80E-05 | 34 | 8.59 | 2.17–34.0 | 2.20E-03 |
| B: Validation set, OS analysis | ||||||||
| Age (years) | 191 | 1.01 | 0.99–1.04 | 0.23 | ||||
| Grade 3 (vs 1+2) | 260 | 1.01 | 0.69–1.50 | 9.50E-01 | ||||
| FIGO stage (IV vs III) | 262 | 2.87 | 1.73–4.77 | 4.71E-05 | 236 | 2.60 | 1.48–4.60 | 9.60E-04 |
| Residual disease (present vs absent) | 235 | 1.59 | 1.07–2.35 | 2.2E-02 | 236 | 1.47 | 0.97–2.22 | 0.07 |
| OPM Unfavourable (vs Favourable) | 262 | 2.42 | 1.6–3.66 | 2.72E-05 | 236 | 2.56 | 1.62–4.03 | 5.40E-05 |
Abbreviations: 95% CI=95% confidence interval; FIGO=Fédération Internationale de Gynécologie et Obstétrique; OPM=optimal prognostic model; OS=overall survival; PFS=progression-free survival.
a
Number of patients with data available. Signficant P-values were highlighted with bold characters.