Table 1. Descriptive characteristics of EAGLE patients whose samples were used in miRNA microarray chip analysisa.
| Characteristic | Adenocarcinoma (n=165) | Squamous cell carcinoma (n=125) |
|---|---|---|
| Median age (range) | 65 (39–79) | 70 (42–80) |
| Gender | ||
| Male | 89 (54%) | 122 (98%) |
| Female | 76 (46%) | 3 (2%) |
| Smoking, n (%) | ||
| Current | 70 (42%) | 64 (51%) |
| Formerb | 61 (37%) | 60 (48%) |
| Never | 34 (21%) | 1 (1%) |
| Average packs per day, median (25th–75th percentile)c | 1.0 (0.75–1.0) | 1.0 (1.0–1.5) |
| Stage, n (%) | ||
| IA | 32 (19%) | 25 (20%) |
| IB | 33 (20%) | 27 (22%) |
| IIA | 10 (6%) | 4 (3%) |
| IIB | 33 (20%) | 38 (30%) |
| IIIA | 32 (19%) | 17 (14%) |
| IIIB | 14 (8%) | 13 (10%) |
| IV | 11 (7%) | 1 (1%) |
Abbreviations: EAGLE=Environment And Genetics in Lung cancer Etiology; miRNA=microRNA.
a
Adapted from Landi et al (2010).
b
Former smokers were subjects who quit smoking ⩾6 months before the study.
c
Data available for current and former smokers only.