Table 2. Comparative 5 and 10 year event rates for luminal A and B.
IBTR
|
LRR
|
DM
|
BCSD
|
|||||
---|---|---|---|---|---|---|---|---|
5 Year (%) | 10 Year (%) | 5 Year (%) | 10 Year (%) | 5 Year (%) | 10 Year (%) | 5 Year (%) | 10 year (%) | |
Whole cohort (n=498) | 12/498 (2.4) | 23/498 (4.6) | 21/498 (4.2) | 35/498 (6.8) | 34/498 (6.8) | 47/498 (9.4) | 18/498 (3.6) | 37/498 (7.4) |
12/24 (50) | 23/24 (95.8) | 21/35 (60) | 35/35 (100) | 34/47 (72.3) | 47/47 (100) | 18/37 (48.6) | 37/37 (100) | |
Luminal A (n=394) | 4/394 (1) | 14/394 (3.6) | 8/394 (2) | 19/394 (4.8) | 19/394 (4.8) | 30/394 (7.6) | 7/394 (1.8) | 23/394 (5.8) |
4/15 (26.6) | 14/15 (93.3) | 8/20 (40) | 19/20 (95) | 19/30 (63.3) | 30/30 (100) | 7/23 (30.4) | 23/23 (100) | |
Luminal B (n=23) | 1/23 (4.3) | 2/23 (8.7) | 1/23 (4.3) | 2/23 (8.6) | 2/23 (8.6) | 2/23 (8.6) | 1/23 (4.3) | 2/23 (8.6) |
1/2 (50) | 2/2 (100) | 1/2 (50) | 2/2 (100) | 2/2 (100) | 2/2 (100) | 1/2 (50) | 2/2 (100) | |
Modified luminal A (n=321) | 2/321 (0.6) | 9/321 (2.8) | 3/321 (0.9) | 11/321 (3.4) | 9/321 (2.8) | 16/321 (4.9) | 1/321 (0.3) | 11/321 (3.4) |
2/9 (22.2) | 9/9 (100) | 3/11 (27) | 11/11 (100) | 9/16 (56.3) | 16/16 (100) | 1/11 (9.1) | 11/11 (100) | |
Modified luminal B (n=96) | 3/96 (3.1) | 7/96 (7.3) | 6/96 (6.3) | 10/91 (10.9) | 12/96 (12.5) | 16/96 (16.7) | 7/96 (7.3) | 14/96 (14.6) |
3/8 (37.5) | 7/8 (87.5) | 6/11 (54.5) | 10/11 (90.1) | 12/16 (75) | 16/16 (100) | 7/14 (50) | 14/14 (100) |
Abbreviations: BCSD=breast cancer-specific death; DM=distant metastasis; ER+ =oestrogen receptor positive; IBTR=ipsilateral breast tumour recurrence; LRR=locoregional recurrence; PR+ =progesterone receptor positive.
Modified luminal A: ER+ and/or PR+, Ki-67 low, p53−, HER2− modified luminal B: ER+ and/or PR+ and/or Ki-67 high and/or p53+ and/or HER2+. In the top row of each box, the denominator is the total number of patients within that patient group or subtype; in the bottom row of each box, the denominator is the total number of events for each group or subtype.