Table 4. ROC curve values for each marker and combination marker by pathology.
CEA ng ml–1 | Total nuclear DNA ng ml–1 plasma | Mitochondrial DNA ng ml–1 plasma | Line1 79/ Line1 300 | Alu 115/247 | Line1 300 ng ml–1 plasma | Alu 247 ng ml–1 plasma | Combined marker | |
---|---|---|---|---|---|---|---|---|
Polyps vs normal | 0.596 | 0.756 | 0.743 | 0.512 | 0.511 | 0.691 | 0.731 | 0.797 |
Cancer vs normal | 0.574 | 0.757 | 0.675 | 0.759 | 0.772 | 0.594 | 0.716 | 0.863 |
Polyps and cancer vs normal | 0.586 | 0.756 | 0.713 | 0.624 | 0.629 | 0.647 | 0.724 | 0.810 |
Abbreviations: CEA=carcinoembryonic antigen; ROC=receiver operator characteristic.