Table 2.
The 60Most Statistically Significant Escherichia coli Genes With Flagellar Propensity Scores Greater Than 1.9 (90% of Max Propensity)
| Locus | Gene | Propensity | p value | t/n | Identification |
|---|---|---|---|---|---|
| b1077 | flgF | 2.15 | 2.950E-11 | 30/30 | +flagellar biosynthesis cell-proximal portion of basal-body rod |
| b1078 | flgG | 2.15 | 2.950E-11 | 30/30 | +flagellar biosynthesis cell-distal portion of basal-body rod |
| b1939 | fliG | 2.15 | 2.950E-11 | 30/30 | +flagellar biosynthesis, component of motor switch and energizing |
| b0229 | fhiA | 1.97 | 5.730E-10 | 33/36 | +polar flagellar assembly protein |
| b1879 | flhA | 1.95 | 8.642E-08 | 30/33 | +flagellar biosynthesis; possible export of flagellar proteins |
| b1880 | flhB | 1.97 | 5.730E-10 | 33/36 | +putative part of export apparatus for flagellar proteins |
| b1948 | fliP | 1.97 | 5.730E-10 | 33/36 | +flagellar biosynthesis protein flip |
| b1938 | fliF | 2.15 | 7.081E-10 | 28/28 | +flagellar biosynthesis; basal-body membrane ring and collar protein |
| b1074 | flgC | 2.08 | 7.231E-10 | 30/31 | +flagellar biosynthesis cell-proximal portion of basal-body rod |
| b1941 | fliI | 1.92 | 4.597E-09 | 33/37 | +flagellum-specific ATPase |
| b1076 | flgE | 2.15 | 1.378E-08 | 26/26 | +flagellar biosynthesis hook protein |
| b1950 | fliR | 2.15 | 1.378E-08 | 26/26 | +flagellar biosynthesis |
| b1884 | cheR | 2.01 | 4.494E-08 | 29/31 | response regulator for chemotaxis; protein glutamate methyltransferase |
| b1887 | cheW | 2.15 | 5.606E-08 | 25/25 | positive regulator of CheA protein activity |
| b1945 | fliM | 2.15 | 5.605E-08 | 25/25 | +flagellar biosynthesis component of motor switch |
| b1080 | flgI | 2.15 | 2.172E-07 | 24/24 | +homolog of Salmonella P-ring of flagella basal body |
| b1883 | cheB | 2.00 | 8.063E-07 | 27/29 | response regulator for chemotaxis (cheA sensor); protein methylesterase |
| b1888 | cheA | 2.07 | 1.113E-06 | 25/26 | sensory transducer kinase between chemo- signal receptors and CheB and CheY |
| b1079 | flgH | 2.15 | 2.863E-06 | 22/22 | +flagellar biosynthesis basal-body outer-membrane L ring protein |
| b1082 | flgK | 2.15 | 9.791E-06 | 21/21 | +flagellar biosynthesis hook-filament junction protein 1 |
| b1890 | motA | 2.15 | 3.187E-04 | 18/18 | +proton conductor component of motor; no effect on switching |
| b0230 | mbhA | 2.15 | 9.560E-04 | 17/17 | * putative motility protein |
| b1889 | motB | 2.15 | 9.560E-04 | 17/17 | +enables flagellar motor rotation, linking torque machinery to cell wall |
| b1924 | fliD | 2.15 | 9.560E-04 | 17/17 | +flagellar biosynthesis; filament capping protein; enables filament assembly |
| b0316 | yahB | 2.15 | 2.789E-03 | 16/16 | putative transcriptional regulator LYSR-type |
| b1659 | ydhB | 2.15 | 2.789E-03 | 16/16 | putative transcriptional regulator LYSR-type |
| b1339 | ydaK | 1.95 | 1.062E-02 | 19/21 | putative transcriptional regulator LYSR-type |
| b0504 | ybbS | 2.03 | 1.179E-02 | 17/18 | putative transcriptional regulator LYSR-type |
| b3105 | yhaJ | 2.02 | 3.211E-02 | 16/17 | putative transcriptional regulator LYSR-type |
| b1925 | fliS | 2.15 | 2.789E-03 | 16/16 | +flagellar biosynthesis; repressor of class 3a and 3b operons (RflA activity) |
| b1946 | fliN | 2.15 | 2.789E-03 | 16/16 | +flagellar biosynthesis, component of motor switch and energizing |
| b0494 | tesA | 2.04 | 4.199E-03 | 18/19 | acyl-CoA thioesterase I; also functions as protease I |
| b0387 | yaiI | 2.15 | 7.921E-03 | 15/15 | orf, hypothetical protein |
| b2213 | ada | 2.15 | 7.921E-03 | 15/15 | O6-methylguanine-DNA methyltransferase; transcription activator/repressor |
| b2681 | 2.15 | 7.921E-03 | 15/15 | putative transport protein | |
| b3686 | glnG | 2.15 | 7.921E-03 | 15/15 | response regulator for gln |
| b3687 | ibpA | 2.15 | 7.921E-03 | 15/15 | heat shock protein |
| b3081 | ygjL | 1.95 | 1.062E-02 | 19/21 | putative NADPH dehydrogenase |
| b0898 | ycaD | 2.03 | 1.179E-02 | 17/18 | putative transport |
| b4119 | melA | 2.03 | 1.179E-02 | 17/18 | alpha-galactosidase |
| b1542 | ydfI | 1.94 | 2.896E-02 | 18/20 | putative oxidoreductase |
| b2172 | yeiQ | 1.94 | 2.896E-02 | 18/20 | putative oxidoreductase |
| b4323 | uxuB | 1.94 | 2.896E-02 | 18/20 | D-mannonate oxidoreductase |
| b1521 | uxaB | 2.02 | 3.211E-02 | 16/17 | altronate oxidoreductase |
| b3356 | yhfA | 1.94 | 2.896E-02 | 18/20 | orf, hypothetical protein |
| b3924 | fpr | 1.94 | 2.896E-02 | 18/20 | ferredoxin-NADP reductase |
| b1256 | yciD | 2.02 | 3.211E-02 | 16/17 | putative outer membrane protein |
| b1813 | yeaB | 2.02 | 3.211E-02 | 16/17 | orf, hypothetical protein |
| b2069 | yegD | 2.02 | 3.211E-02 | 16/17 | putative heat shock protein |
| b3775 | ppiC | 2.02 | 3.211E-02 | 16/17 | peptidyl-prolyl cis-trans isomerase C (rotamase C) |
| b0610 | rnk | 2.15 | 5.931E-02 | 13/13 | regulator of nucleoside diphosphate kinase |
| b1075 | flgD | 2.15 | 5.931E-02 | 13/13 | +flagellar biosynthesis, initiation of hook assembly |
| b1083 | flgL | 2.15 | 5.931E-02 | 13/13 | +flagellar biosynthesis; hook-filament junction protein |
| b1688 | 2.15 | 5.931E-02 | 13/13 | orf, hypothetical protein | |
| b2922 | yggE | 2.15 | 5.931E-02 | 13/13 | putative actin |
| b3010 | yqhC | 2.15 | 5.931E-02 | 13/13 | putative ARAC-type regulatory protein |
| b3328 | hofG | 2.15 | 5.931E-02 | 13/13 | putative general protein secretion protein |
| b4355 | tsr | 2.15 | 5.931E-02 | 13/13 | methyl-accepting chemotaxis protein I, serine sensor receptor |
| b1073 | flgB | 2.02 | 8.488E-02 | 15/16 | +flagellar biosynthesis, cell-proximal portion of basal-body rod |
The genes marked with + in the identification column are know flagellar genes. t is the number of flagellar bacteria that contain homologs to the gene, and n is the total number of genomes that contain homologs to the gene. Genes in adjacent shaded rows are paralogs.