Table 4.
The 40Most Statistically Significant T. tengcongensis Proteins With Thermophily Propensity Scores Greater Than 3.0
| Locus | Gene | Propensity | p value | t/n | Identification |
|---|---|---|---|---|---|
| TTE2470 | MesJ4 | 5.38 | 2.40E-12 | 15/16 | predicted ATPase of the PP-loop superfamily implicated in cell cycle control |
| TTE0073 | MesJ | 5.06 | 1.65E-11 | 15/17 | predicted ATPase of the PP-loop superfamily implicated in cell cycle control |
| TTE0285 | 5.73 | 9.29E-12 | 14/14 | conserved hypothetical protein | |
| TTE1955 | PflA2 | 4.78 | 9.78E-11 | 15/18 | Pyruvate-formate lysase-activating enzyme (protein modification & repair) |
| TTE0474 | Gcd14 | 4.30 | 1.84E-09 | 15/20 | predicted SAM-dependent methyltransferase involved in tRNA-Met maturation |
| TTE1745 | rgy | 5.73 | 7.71E-09 | 12/12 | Reverse gyrase (DNA replication, recombination, and repair) |
| TTE1895 | SmtA4 | 5.29 | 9.63E-08 | 12/13 | SAM-dependent methyltransferases |
| TTE2198 | PorA6 | 3.58 | 1.55E-07 | 15/24 | ferredoxin oxidoreductase, alpha subunit (anaerobic metabolism) |
| TTE1209 | PorA3 | 3.34 | 1.46E-05 | 14/24 | ferredoxin oxidoreductase, alpha subunit (anaerobic metabolism) |
| TTE1340 | PorA4 | 3.34 | 1.46E-05 | 14/24 | ferredoxin oxidoreductase, alpha subunit (anaerobic metabolism) |
| TTE0961 | PorA2 | 3.39 | 1.22E-04 | 13/22 | 2-oxoacid ferredoxin oxidoreductase, alpha subunit (fermentation) |
| TTE1354 | SpeD | 4.01 | 3.05E-07 | 14/20 | S-adenosylmethionine decarboxylase (polyamine biosynthesis) |
| TTE1210 | PorB2 | 3.44 | 3.88E-07 | 15/25 | ferredoxin oxidoreductase, beta subunit (anaerobic metabolism) |
| TTE1341 | PorB3 | 3.44 | 3.88E-07 | 15/25 | ferredoxin oxidoreductase, beta subunit (anaerobic metabolism) |
| TTE1276 | Nfo | 4.91 | 6.50E-07 | 12/14 | Endonuclease IV (DNA degradation) |
| TTE1779 | PflX | 4.85 | 1.02E-05 | 11/13 | pyruvate formate lyase activating enzyme (protein modification and repair) |
| TTE0960 | PorB | 3.34 | 1.46E-05 | 14/24 | 2-oxoacid ferredoxin oxidoreductase, beta subunit (fermentation) |
| TTE1571 | 3.73 | 2.01E-05 | 13/20 | conserved hypothetical protein | |
| TTE2189 | 3.24 | 2.72E-04 | 13/23 | conserved hypothetical protein | |
| TTE2193 | PorG3 | 4.50 | 4.50E-05 | 11/14 | indolepyruvate ferredoxin oxidoreductase, beta subunit |
| TTE1537 | HypE3 | 3.09 | 6.99E-05 | 14/26 | Hydrogenase maturation factor (electron transport) |
| TTE2532 | 3.82 | 1.13E-04 | 12/18 | predicted Zn-dependent hydrolases of beta-lactamase fold | |
| TTE0444 | 5.73 | 3.13E-04 | 8/8 | conserved hypothetical protein | |
| TTE1518 | LigT | 5.73 | 3.13E-04 | 8/8 | 3-5 RNA Ligase (cell envelope: synthesis of murein sacculus & peptidoglycan) |
| TTE0818 | GltB | 4.69 | 1.34E-03 | 9/11 | Glutamate synthase domain 3 (methanogenesis) |
| TTE1866 | 3.28 | 1.58E-03 | 12/21 | conserved hypothetical protein | |
| TTE0714 | 5.10 | 2.59E-03 | 8/9 | putative integrase-resolvase (DNA replication, recombination, repair) | |
| TTE2659 | 5.10 | 2.59E-03 | 8/9 | putative RecB family exonuclease | |
| TTE0820 | GltB3 | 5.73 | 3.11E-03 | 7/7 | amidophophoribosyltransferase (purine ribonucleotide synthesis) |
| TTE1891 | 5.73 | 3.11E-03 | 7/7 | MinD P-loop ATPase containing an inserted ferredoxin domain (electron transport) | |
| TTE1892 | 5.73 | 3.11E-03 | 7/7 | MinD P-loop ATPase containing an inserted ferredoxin domain (electron transport) | |
| TTE1893 | 5.73 | 3.11E-03 | 7/7 | conserved hypothetical protein | |
| TTE1898 | 5.73 | 3.11E-03 | 7/7 | predicted methyltransferases | |
| TTE2657 | 5.73 | 3.11E-03 | 7/7 | conserved hypothetical protein | |
| TTE0705 | 4.59 | 1.20E-02 | 8/10 | putative integrase-resolvase (DNA replication, recombination, repair) | |
| TTE0715 | 4.59 | 1.20E-02 | 8/10 | predicted transposase | |
| TTE1551 | Dap2 | 3.97 | 1.50E-02 | 9/13 | putative acyl-peptide hydrolase |
| TTE2658 | 3.97 | 1.50E-02 | 9/13 | conserved hypothetical protein | |
| TTE2633 | 5.02 | 2.26E-02 | 7/8 | conserved hypothetical protein | |
| TTE2194 | PorA5 | 3.37 | 2.72E-02 | 10/17 | indolepyruvate ferredoxin oxidoreductase, alpha subunit |
t is the number of thermophiles that contain homologs to the protein, and n is the total number of genomes that contain homologs to the protein. Genes in adjacent shaded rows are paralogs.