Figure 3.

Base-specific cleavage spectra leading to the discovery of a G/A polymorphism at nucleotide position 13490 of the CETP gene (SNP #11 in Table 2).For each cleavage reaction, the spectral changes expected to result from the proposed SNP and the experimental results are shown.The spectra of a representative homozygous wt sample are matched with the spectra of the single heterozygous sample in which the mutation was found.Arrows indicate the wt and the mutation-specific peaks.