Table 1.

Summary of angiotensin converting enzyme expression by cardiac vessels and cardiomyocytes in the different genetic models.

Tissue site	Genetic model
	KO	8/8	1/8	WT/8	WT
	n=15	n=15	n=11	n=13	n=40
Vascular ACE	-	-	-	0.5+	1+
Cardiomyocyte ACE	-	100+	50+	50+	-
ACE activity (% of WT level)
Plasma	-	56%	23%	75%	100%
Lung	-	43%	30%	79%	100%

The level of angiotensin converting enzyme (ACE) expression by vessels and cardiomyocytes is shown in relation to a level of vascular ACE expression in WT mice of 1+. ACE was undetectable by immunocytochemistry in vessels of 8/8 and 1/8 mice, and in cardiomyocytes of WT mice. Data from previously published studies.^14-16