Table 2.

Oxidative stress markers, and hemoglobin changes in four groups of study patients

Study period			P*	Estimated means* (3weeks)	Pariwise significant results (LSD)
	Baseline	3weeks
Hb(mg/dl)
1.control	11.01±2.58	10.92±1.68	0.002	11.05	2,3,4 vs.1
2.silymarin	10.93±1.53	12.55±1.79		12.72
3.vit E	11.29±2.46	12.61±2.18		12.60
4.combined	11.88±1.63	12.68±1.90		12.36
GPX(Iu/gr-Hb)
1.control	5.62±2.85	3.16±1.89	0.001	2.70	2,3,4 vs.1 & 4 vs.3
2.silymarin	3.52±1.54	4.28±1.94		4.51
3.vit E	3.93±2.18	4.22±1.63		4.43
4.combined	3.98±2.03	5.78±3.51		5.89
MDA(nmol/ml)
1.control	7.82±1.56	9.20±2.74	0.049	9.64	4 vs.1
2.silymarin	9.67±3.08	9.40±2.54		9.12
3.vit E	9.08±2.83	8.42±2.63		8.38
4.combined	9.27±2.62	7.84±1.84		7.71

^*Based on ANCOVA: 3 week measurement of each variable as “dependent” and “baseline” as “covariate” (significance level= 0.05)

GPX=Glutathione peroxidase, MDA=Malondialdehyde, Hb=Hemoglobin