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. 2010 Dec 7;1(2):155–167.

Figure 6.

Figure 6

Inhibition of Akt expression results in decreased proliferation and increased apoptosis. Tumors were induced by injection of KRas, Tet-off and TRE-Akt viruses in the brains of Nestin-TVA mice, which were left untreated (A, C and E) or were treated with doxycycline for 24 hours (B, D and F). (A-B) IHC for the proliferation marker Ki67. (C-D) Representative H&E stained 5 μm brain histology sections. (E-F) TUNEL staining to assess apoptosis. Scale bar represents 100 μm.