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[Figure 6B:] The two mutations, agAT > cgAT (IVS12-2 a>c) and agAT > ggAT (IVS12-2 a>g), weaken this site sufficiently that the mutated exon 12 begins at location 77670, initiated by a formerly cryptic acceptor site of strength 6.8 bits 70 bp upstream. Several weaker acceptor sites between these two are neither used nor modified.
