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. Author manuscript; available in PMC: 2011 Jul 25.
Published in final edited form as: Expert Rev Neurother. 2010 Oct;10(10):1595–1605. doi: 10.1586/ern.10.133

Table 1.

α-2A adrenergic influences on prefrontal cortical functions.

Prefrontal cortex operation Ref.
Improve working memory [48,57,73,75,145,146]

Attention regulation:
• Reduce distractibility [74,147]
• Improve sustained attention [117]
Strengthen behavioral inhibition
• Cognitive:
 – Stroop interference [148]
 – No-go performance [82]
• Emotional:
 – Reward reversal [80]

High-order associative learning [149]

Planning and organization [75]