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. 2011 Jul 6;31(27):9789–9799. doi: 10.1523/JNEUROSCI.0901-11.2011

Figure 4.

Figure 4.

Immunofluorescence and in situ hybridization of novel Brn3a/Islet1 DKO targets. Cervical DRG of E12.5 embryos were examined in single KO, DKO, and control embryos. Antisera for Islet2, Prrxl1, and Brn3b confirmed the loss of these transcription factors in DKO ganglia, while the marker of glial precursors Sox10 was unaffected. Dashed lines indicate the location of DRG in sections in which the signal cannot be clearly distinguished from background.