Figure 2.

Male and female astrocytes show a different response to LPS. mRNA levels of IL6, IP10, TNFα and IL1β in lipopolysaccharide (LPS)-treated cortical astrocyte cultures from male and female mouse pups are shown. Data are means ± SEM and are expressed as percentages of controls (red line indicates astrocytes cultured with control medium without LPS). **P < 0.01 and ***P < 0.001, indicating significant differences compared with female values. +P < 0.05 and +++P < 0.001, indicating significant differences compared with cultures not treated with LPS.