Table 4.
Biological functions affected by inoculation solely
| E. coli | S. aureus | |||||
|---|---|---|---|---|---|---|
| Top 5 categories of biological functions | SCS-BTA18-Q | SCS-BTA18-q | SCS-BTA18-Q | |||
| E. coli versus control SCS-BTA18-Q | p-values | Genes | p-values | Genes | p-values | Genes |
| Cell death | 1,08E-13 | 96 | 8,30E-05 | 18 | 5,00E-05 | 14 |
| Cell-to-cell signaling and interaction | 3,60E-13 | 51 | 5,35E-03 | 12 | 2,45E-04 | 7 |
| Hematological system development and function | 3,60E-13 | 53 | 7,87E-05 | 14 | 8,09E-05 | 8 |
| Immune cell trafficking | 3,60E-13 | 34 | 8,62E-04 | 7 | 8,09E-05 | 5 |
| Tissue development | 3,60E-13 | 38 | 6,51E-03 | 5 | 3,49E-03 | 4 |
| E. coli | S. aureus | |||||
| Top 5 categories of biological functions | SCS-BTA18-Q | SCS-BTA18-q | SCS-BTA18-Q | |||
| E. coli versus control SCS-BTA18-q | p-values | Genes | p-values | Genes | p-values | Genes |
| Hematological system development and function | 3,60E-13 | 53 | 7,87E-05 | 14 | 8,09E-05 | 8 |
| Hematopoesis | 8,87E-07 | 27 | 7,87E-05 | 9 | 1,03E-04 | 5 |
| Cell death | 1,08E-13 | 96 | 8,30E-05 | 18 | 5,00E-05 | 14 |
| Cellular development | 1,67E-07 | 56 | 9,58E-05 | 11 | 1,52E-05 | 9 |
| Gene expression | 3,39E-11 | 81 | 1,25E-04 | 10 | 1,11E-03 | 10 |
| E. coli | S. aureus | |||||
| Top 5 categories of biological functions | SCS-BTA18-Q | SCS-BTA18-q | SCS-BTA18-Q | |||
| S. aureus versus control SCS-BTA18-Q | p-values | Genes | p-values | Genes | p-values | Genes |
| Inflammatory response | 4,38E-11 | 51 | 3,63E-03 | 11 | 8,30E-06 | 7 |
| Cellular development | 1,67E-07 | 56 | 9,58E-05 | 11 | 1,52E-05 | 9 |
| Cellular growth and proliferation | 9,89E-12 | 112 | 5,35E-03 | 18 | 1,52E-05 | 15 |
| Tissue morphology | 5,40E-05 | 13 | 6,51E-03 | 2 | 4,12E-05 | 3 |
| Cell death | 1,08E-13 | 96 | 8,30E-05 | 18 | 5,00E-05 | 15 |
Top 5 biological functions affected between inoculated SCS-BTA18-Q and SCS-BTA18-q cells and respective control cells; the functional category, p-values and the number of genes are shown for E. coli inoculated SCS-BTA18-Q and SCS-BTA18-q cells and S. aureus inoculated SCS-BTA18-Q cells; the categories are ranked by p-values of the SCS-BTA18-Q and SCS-BTA18-q cells, respectively and related p-values and the number of involved genes are shown for the alternative QTL allele and pathogen; for S. aureus inoculated SCS-BTA18-q cells the number of significantly differentially expressed genes was to low to perform a reliable investigation of associated molecular and cellular functions.