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The expression of PPAR-γ in cultured synoviocytes. (a) Untreated cultured synoviocytes. Synoviocytes expressed fibroblastoid morphology. Immunoreactive PPAR-γ was localized in cytoplasmic region and nucleus, but predominantly in the cytoplasmic region in some synoviocytes. (b) Synoviocytes treated with 15d-PGJ2 (10 μM, 12 hours). Synoviocytes appeared less active and had an irregular or round shape, with nuclear translocation of PPAR-γ. ×100.
