Figure 4. Sequence conservation between J domains from the human ERdj proteins and from P58^IPK from different species.

(A) Alignment of sequences of the J domains from the human ERdj proteins. The surface residues mentioned in the text are labelled, using (*) for the residues of the conserved HPD motif, (#) for residues of the adjacent hydrophobic patch in human P58^IPK, and (§) for positively charged residues on helix II. Conserved residues are shown with red background, and residue numbering corresponds to human P58^IPK. (B) Sequence alignment of the J domains from P58^IPK from different species. Labelling is the same as in (A).