Table 1. Rationale for the selection of the miR-SNPs analyzed.
| Location | Gene | rs NCBI(AB assay ID) | Rationale * |
| miRNA genes | MIR194-2 | rs11231898(C__32062040_10) | miR-194 is differentially expressed in lung cancer [11] * |
| MIR196A2 | rs11614913(C__31185852_10) | Risk of head and neck, breast, lung and gastric cancers [25], [27], [44], [45]Poor survival in lung cancer [23] | |
| MIR149 | rs2292832(C__11533078_1_) | miR-149 is differentially expressed in prostate cancer [46] | |
| MIR423 | rs6505162(C__11613678_10) | Risk of bladder cancer [47]Decreased risk esophageal cancer [48] | |
| MIR146A | rs2910164(C__15946974_10) | Risk of papillary thyroid carcinoma [49]Risk of hepatocarcinoma [50]Risk of prostate cancer [51] | |
| miRNA binding sites | KRT81 | rs3660(C__11917951_20) | miRNA-binding SNPs with an aberrant SNP allele frequency in human cancers [36] |
| FAM179B | rs1053667(C__11606996_1_) | miRNA-binding SNPs with an aberrant SNP allele frequency in human cancers [36] | |
| AFF1 | rs17703261(C__32818766_10) | miRNA-binding SNPs with an aberrant SNP allele frequency in human cancers [36] | |
| miRNA-processing machinery | XPO5 | rs11077(C___3109165_1_) | Risk of esophageal cancer [48] |
| RAN | rs14035(C__11351340_10) | Risk of esophageal cancer [48] | |
| TRBP | rs784567(C___9576934_20) | Risk of bladder cancer [47] |
*One of the selection criteria was a described association with a differential susceptibility to cancer development. In MIR194-2, the association was with the miRNA containing the SNP, while in all other cases, the association was with the miR-SNP itself.