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. 2011 Jul 25;6(7):e22667. doi: 10.1371/journal.pone.0022667

Figure 3. Pro-inflammatory mediators in Ada -/- mice treated with IL-6 neutralizing antibodies.

Figure 3

Transcript levels of various pro-inflammatory cytokines and chemokines were measured in whole-lung RNA extracts from postnatal day 43 mice using quantitative RT-PCR. Shown are levels of (A) CXCL-1, (B) MCP-1, (C) OPN, (D) IL-17, (E) MIP-2, and (F) TNF-α. Transcripts were measured in parallel with 18S rRNA and values are presented as mean normalized transcript levels (Δ−ct) ±SEM, n≥4. *, p≤0.05 Ada + vs Ada -/- and #, p≤0.05 Ada -/- vs Ada -/- + Anti-IL-6.